Black Women Underrepresented in HIV Clinical Studies

In a study of HIV-infected women presenting for prenatal care, non-Hispanic black women were less likely than other groups to enroll in a clinical research study.

Previous studies have shown that women of color are often underrepresented in clinical trials of antiretroviral therapy. Enrollment of nonrepresentative patient populations, as a result of either patient choice or provider selection, can bias study results and generate conclusions with limited applicability. To shed light on this issue, investigators evaluated rates and reasons for nonenrollment in a large prospective cohort study on interventions to prevent mother-to-child HIV transmission and to protect maternal health.

Of the 2752 HIV-infected pregnant women who presented for prenatal care at the 48 study sites, 1783 were randomized to be approached for study enrollment (randomization was intended to prevent selective enrollment). At the …

Reviewing Author

Holly Rawizza, MD

Black Women Underrepresented in HIV Clinical Studies

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Reviewing Author