Serious Non-AIDS Events in HIV-Infected Patients

Such events are common in the modern HIV-treatment era and are associated with increased mortality.

Non-AIDS clinical events have become important contributors to morbidity and mortality among HIV-infected patients, as demonstrated in a recent analysis from the EuroSIDA study.

The analysis involved 12,844 HIV-infected patients (73% men; 88% white) who had prospective follow-up of any duration between 2001 and mid-2009. At baseline, median age was 39, and median CD4 nadir was 178 cells/mm³. More than 80% of patients were receiving potent antiretroviral therapy. Approximately 40% of patients were homosexual, 23% were injection-drug users, 24% were hepatitis C virus–positive, and 6% were hepatitis B virus–positive.

The incidence of AIDS events was 1.72 per 100 person-years of follow-up, while the incidence of non-AIDS events (renal disease, li…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Serious Non-AIDS Events in HIV-Infected Patients

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Reviewing Author