Vitamin D Insufficiency in HIV-Infected Patients

Vitamin D insufficiency was slightly less common in HIV-infected patients than in the general U.S. population. The clinical significance of this insufficiency remains uncertain.

Vitamin D deficiency is associated with a broad range of disorders, many of which are also linked to HIV infection and its treatment. However, little is known about the prevalence or predictors of low vitamin D levels among HIV-infected adults.

To address this gap, researchers evaluated laboratory, clinical, and behavioral data from 672 HIV-infected patients who were part of a larger U.S. cohort study and were not receiving vitamin D supplementation. Vitamin D insufficiency was defined as a 25-hydroxyvitamin D level <30 ng/mL, and prevalence estimates were standardized by age, sex, and race.

Seventy percent of the HIV-infected population was estimated to have vitamin D insufficiency. By comparison, the estimated prevalence in the general U.S.…

Reviewing Authors

Eileen Scully, MD, PhD

Paul E. Sax, MD

Disclosures

Consultant/Advisory BoardGilead Sciences; GlaxoSmithKline/ViiV; Merck; Shionogi

Grant/Research SupportNIH; Gilead Sciences; ViiV

Editorial BoardsUpToDate; Clinical Infectious Diseases