A randomized trial confirms that treatment IS prevention.
Treating HIV-infected individuals dramatically reduces the likelihood that they will transmit the virus to their sexual partners, according to findings just released from an interim analysis of the HPTN 052 study.
A total of 1763 HIV-serodiscordant couples (97% heterosexual) participated in this study, which took place in Africa, Asia, and the Americas. The HIV-infected partners in these couples had CD4 counts between 350 and 550 cells/mm3 at enrollment; half were randomized to start antiretroviral therapy (ART) immediately, and half were randomized to wait until their CD4 counts dropped below 250 cells/mm3 or an AIDS-related illness occurred. All couples received free condoms, behavioral counseling, and treatment for sexually transmitted in…
Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)