Non-AIDS Events A Major Problem for Patients Receiving ART in Africa

Such events caused 30% of all deaths in a cohort of patients receiving ART in Botswana versus 4% of deaths in a U.S. cohort.

In resource-rich countries, non–AIDS-defining events have emerged as the leading cause of morbidity and mortality among HIV-infected patients receiving antiretroviral therapy (ART). Whether such events are also important among patients taking ART in resource-limited settings is unknown.

To explore this issue, researchers compared the incidence of non–AIDS-defining events in 2002–2007 between two cohorts of adults taking ART: an observational cohort in Nashville, Tennessee (n=1129) and a clinical-trial cohort in an urban area of Botswana (n=650). The main criteria for starting ART in Botswana were similar to those in the U.S. at the time. The two cohorts differed significantly with respect to age (median, 33 in the Botswana cohort vs. 40 in t…

Reviewing Author

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Keith Henry, MD

Disclosures

Consultant/Advisory BoardViiV Advisory Board

Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes

Non-AIDS Events A Major Problem for Patients Receiving ART in Africa

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Reviewing Author