One in five treatment-eligible HIV-infected individuals at a South African clinic refused to initiate ART, mainly because they were “feeling healthy.”
South Africa has the largest antiretroviral therapy (ART) program in the world, but many patients who are eligible for ART have not yet initiated it. Failure to present for treatment likely plays a role, but so does treatment refusal. In the present study, researchers evaluated the rates and reasons for such refusal within an HIV treatment and care program in Soweto, South Africa.
Of the 7287 adults tested for HIV between December 2008 and December 2009, 35% were found to be HIV-infected, and almost a third (29%) were eligible for immediate ART (CD4 count <200 cells/mm3 or WHO stage 4 disease). Of these eligible individuals, 20% refused treatment, with the most common reason being that they “felt healthy.” Other reasons included fear of disc…
Reviewing Author
DisclosuresConsultant/Advisory BoardUNAIDS; WHO; Bill and Melinda Gates Foundation, Population Council
Grant/Research SupportNIH; National Institute of Allergy and Infectious Diseases; Tides Foundation/MAC AIDS Fund; USAID; South African National Research Foundation; European Union; South African Medical Research Council
Editorial BoardsNew England Journal of Medicine; AIDS Reviews; AIDS Research and Human Retroviruses; mBio; Indian Journal of Medical Research; JAIDS: Journal of Acquired Immune Deficiency Syndromes
DisclosuresConsultant/Advisory BoardUNAIDS; WHO; Bill and Melinda Gates Foundation, Population Council
Grant/Research SupportNIH; National Institute of Allergy and Infectious Diseases; Tides Foundation/MAC AIDS Fund; USAID; South African National Research Foundation; European Union; South African Medical Research Council
Editorial BoardsNew England Journal of Medicine; AIDS Reviews; AIDS Research and Human Retroviruses; mBio; Indian Journal of Medical Research; JAIDS: Journal of Acquired Immune Deficiency Syndromes