The OraQuick rapid HIV test performed well on both types of samples but was less sensitive and specific on oral fluid, which would lead to a lower positive predictive value in low-prevalence settings.
Global attention on the HIV epidemic is focused on the potential synergistic treatment and prevention benefits of “test and treat.” With this strategy, the gateway to improved clinical outcomes and epidemic control is the HIV test. Only a few such tests offer both oral fluid and fingerstick sampling options, and of these, the OraQuick test is the most frequently used. Although data on the performance of this test are available from the manufacturer, they do not provide test characteristics from real-life settings.
To fill this gap, researchers conducted a systematic review and meta-analysis of studies (mostly from the U.S.) that used the OraQuick Advance Rapid HIV-1/2 test. Three types of studies were included: those that compared oral and f…
Reviewing Author
Rochelle P. Walensky, MD, MPH
Rochelle P. Walensky, MD, MPH