Higher baseline fibrosis stages were associated with higher all-cause mortality and liver-related mortality, whereas ART use was associated with lower mortality.
Patients coinfected with HIV and hepatitis C virus (HCV) are at greater risk for premature death than HCV-monoinfected patients, in part because they tend to have more rapidly progressive liver disease. In the present study, researchers quantified the mortality risk associated with various stages of liver fibrosis in HIV/HCV-coinfected patients and also evaluated the effects of HIV and HCV treatment.
The study population consisted of 638 HIV/HCV-coinfected adults who were followed at an urban HIV clinic and had baseline liver biopsy data available (80% black, 66% male, 76% with a history of injection-drug use, and 47% with a history of alcohol abuse). At the time of initial liver biopsy, the patients were relatively young (median age, 46), m…
Reviewing Author
DisclosuresNothing to disclose
DisclosuresNothing to disclose