In this Image in Clinical Medicine in the New England Journal of Medicine, scattered pink papillomatous lesions are seen on the right ventral surface of a healthy adult patient’s tongue.
The authors describe a healthy young-adult woman who presented with a 3-month history of pink papillomatous lesions on the right ventral surface of her tongue. These lesions were initially presumed to be condyloma acuminatum, skin growths caused by the human papillomavirus (HPV). However, HPV testing was negative, and histopathology showed macrophages, confirming the diagnosis of oral verruciform xanthomas.
Although the patient’s lesions look like condyloma acuminatum, clinicians should have a broad differential diagnosis in mind, including skin cancer and verruciform xanthomas. Oral verruciform xanthomas are rare, benign lesions that appear as well-circumscribed, papillary verrucous or granular plaques or nodules. Patients generally …
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The authors describe a healthy young-adult woman who presented with a 3-month history of pink papillomatous lesions on the right ventral surface of her tongue. These lesions were initially presumed to be condyloma acuminatum, skin growths caused by the human papillomavirus (HPV). However, HPV testing was negative, and histopathology showed macrophages, confirming the diagnosis of oral verruciform xanthomas.
Although the patient’s lesions look like condyloma acuminatum, clinicians should have a broad differential diagnosis in mind, including skin cancer and verruciform xanthomas. Oral verruciform xanthomas are rare, benign lesions that appear as well-circumscribed, papillary verrucous or granular plaques or nodules. Patients generally …