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Patients with Parkinson disease often develop symptoms related to overactive bladder, including urgency, nocturia, and incontinence. These symptoms create more than just inconvenience: They predispose patients to falling and affect quality of life. In this 12-week trial, researchers randomized 77 patients with Parkinson disease and overactive bladder symptoms to receive either drug therapy (i.e., the anticholinergic solifenacin) or behavioral therapy that involved pelvic floor muscle exercises, urge suppression techniques, and other standard behavioral measures.
On a standardized 16-point overactive-bladder questionnaire, mean scores improved from a baseline of ≈9 to ≈6 in both groups (see ); this 3-point improvemen…