Can Non-MRI Amyloid Angiopathy Criteria Predict Intracerebral Hemorrhage Recurrence?

Clinicians typically diagnose cerebral amyloid angiopathy (CAA) after a patient presents with a lobar intracerebral hemorrhage (ICH) and MRI demonstrates cortical microbleeds. However, in some parts of the world, MRI is not readily available and other techniques to identify CAA would be useful. These authors performed a meta-analysis using pooled data from several longitudinal studies that had CT and apolipoprotein E (APOE) data available. They used the Edinburgh computed tomography (CT) criteria to classify a patient’s risk for CAA and, therefore, recurrent ICH, as low (neither subarachnoid hemorrhage nor “finger-like” projections from the hematoma), medium (one or the other feature) or high (both features). They also considered CT …