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After the large clade IIb mpox outbreak in 2022, mpox continues to circulate at low levels in the United States. Now, evidence points to community transmission of clade Ib in five cases in California with no epidemiologic link to each other. While the clinical outcomes of mpox have been well described in the general public, outcomes of infections during pregnancy have only been described in few small case series.
To fill this gap, investigators in the Democratic Republic of Congo (DRC) pooled data from four prospective studies to evaluate the adverse outcomes associated with polymerase chain reaction (PCR)-confirmed mpox during pregnancy. Some 72% of the infections were in areas where clade Ib was prevalent, and 28% were in clade Ia-p…