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The health effects of low levels of alcohol consumption remain controversial. Large observational studies have suggested cardiovascular benefits at low levels of drinking, whereas recent public health guidance has questioned whether any level of alcohol consumption is risk-free (). Investigators used a modeling approach based on U.S. data to estimate alcohol-related risk across the full spectrum of alcohol consumption, with the goal of better characterizing risk within categories traditionally considered low-risk.
Low levels of alcohol consumption were not associated with a significant net health benefit.
Excess alcohol-attributable mortality was significant at about 2 drinks per day in both men and women (about 4 in…