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The Acute Decompensated Heart Failure National Registry is a prospective database of patient information beginning with the initial point of care, either in the hospital or emergency department, and continuing until patient discharge, transfer, or death. Researchers retrospectively evaluated this data to determine if admission B-type natriuretic peptide (BNP) level predicted in-hospital mortality in patients with acute decompensated heart failure.
The 48,629 BNP measurements obtained within 24 hours of presentation were divided into quartiles: Q1 (<430 pg/mL), Q2 (430–839 pg/mL), Q3 (840–1729 pg/mL), and Q4 (≥1730 pg/mL). Mortality rate increased linearly with increasing BNP level. Depending on adjustments made in the analyses, the odds rati…