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Historically, venous thromboembolic diseases (deep venous thrombosis [DVT] and pulmonary embolism [PE]) and arterial thromboembolic diseases (stroke and myocardial infarction) have been thought to have separate pathophysiologies and risk factors, but some studies have shown an association between the two entities. In a 20-year population-based cohort study, researchers used data from a Danish national medical database to assess risk for MI and stroke in patients with DVT (25,199) and PE (16,925) compared with controls (163,566). Patients with existing hypertension, cerebrovascular disease, or heart disease were excluded from analysis.
Overall, patients with DVT had a relative risk for MI during the first year of 1.60 and an RR for stroke of …