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Young infants with febrile urinary tract infection (UTI) often are hospitalized for inpatient treatment because of a purported high risk for bacteremia and renal scarring. These authors examined the feasibility of outpatient treatment with intravenous antibiotics in a convenience sample of 67 well-appearing 30- to 90-day-old infants who presented to an emergency department in Montreal with fever and had urinalysis results consistent with a diagnosis of UTI.
The infants received initial treatment in the ED followed by daily treatment in an outpatient center with gentamicin (5 mg/kg) administered intravenously (or intramuscularly when IV access failed) until the child was afebrile for at least 24 hours and initial urine culture results were av…