Loading...
In a prospective, randomized study of children receiving intramuscular (IM) ketamine for laceration repair at a Korean emergency department (ED), researchers determined the incidence of ketamine-associated vomiting and evaluated the effect of adjunctive atropine or metoclopramide. During a 1-year period, 338 children aged 4 months to 5 years received a single IM injection of ketamine (4 mg/kg), alone or with IM atropine (0.01 mg/kg) or IM metoclopramide (0.04 mg/kg).
The incidence of ketamine-associated vomiting did not differ among the three groups either in the ED or within 24 hours after discharge; the combined ED and postdischarge incidence was 28% with ketamine alone, 28% with ketamine plus atropine, and 31% with ketamine plus metoclopr…