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Investigators assessed the diagnostic performance of computed tomography (CT) and ultrasound in relation to symptom duration in children (age range, 3 to 18 years) with suspected appendicitis. This secondary analysis of a prospective study of patients who presented to one of nine pediatric emergency departments included only patients with abdominal pain for <72 hours. Symptom duration was categorized as <12 hours, 13 to 24 hours, 25 to 36 hours, 37 to 48 hours, or 49 to 71 hours.
Of 1810 patients, 67% underwent CT, and 46% underwent ultrasound. Overall, 680 patients (38%) had pathology-confirmed appendicitis, and of these patients, 174 (26%) had perforated appendicitis. The sensitivity of CT for diagnosing appendicitis did not differ signifi…