Outcomes of TB Treatment in HIV-Infected Patients

Relapse rates were significantly higher in TB patients with HIV infection than in those without such infection.

Current guidelines for treating drug-susceptible TB recommend a 6-month rifamycin-based regimen, regardless of the patient’s HIV serostatus. Is 6 months long enough in HIV-infected patients?

To find out, researchers conducted a retrospective cohort study among 700 patients with culture-proven TB whose cases were reported to the San Francisco Tuberculosis Control Program from 1990 through 2001. Among these patients, 264 (38%) were known to be HIV-infected, and 315 (45%) were known to be uninfected; 121 (17%) had no risk factors for HIV and were not offered testing. Compared with the HIV-uninfected/unknown patients, the HIV-infected patients were significantly younger, more likely to be male and U.S.-born, and more likely to have had both pulm…

Reviewing Author

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Neil M. Ampel, MD

Disclosures

Editorial BoardsUpToDate

Leadership Positions in Professional SocietiesCoccidioidomycosis Study Group (Past President, Secretary, Treasurer)

Outcomes of TB Treatment in HIV-Infected Patients

Topics

Reviewing Author