Risk Factors for albicans and Non-albicans Candidemia

Surgery, hemodialysis, bacteremia, parenteral nutrition, and transfusions were associated with both albicans and non-albicans candidemia.

Candida species are a common cause of bloodstream infections (BSIs) in critically ill patients. Fluconazole, which is frequently used for treatment and prophylaxis of fungal infections, is more active against Candida albicans than against several non-albicans species. Distinguishing between the risk factors for albicans and for non-albicans BSIs might therefore help to guide prophylactic treatment.

To examine these risk factors, researchers performed a retrospective case-control study involving ICU patients at two Boston hospitals between 1995 and 2005. Sixty-seven patients with non–C. albicans and 79 patients with C. albicans BSIs were identified and compared to 780 matched controls without candidemia. The non-albicans Candida species isol…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection