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In recent years, sensitive molecular testing has revealed that rhinoviruses may play a role in respiratory infections beyond the common cold. Now, investigators have linked rhinoviruses to severe lower respiratory tract infections (LRTIs) in children.
Upper respiratory tract samples (nasopharyngeal washes or swabs) were collected from 43 patients aged <18 years consecutively admitted with community-acquired LRTIs to the ICU of a California children’s hospital. If available, lower respiratory tract specimens (endotracheal aspirates, bronchoalveolar lavage fluids, or pleural fluids) were also tested. Specimens were subjected to direct fluorescence antibody testing for influenza viruses and respiratory syncytial virus (RSV) and to real-time PCR…