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Although maternal primary cytomegalovirus (CMV) infection frequently causes severe complications in the fetus, the consequences of perinatally acquired CMV infection are still unclear. Most CMV-seropositive mothers shed CMV in their breast milk. Limited studies suggest that infections acquired through breast milk usually remain asymptomatic in full-term infants, but what is the situation with premature infants, who are at greater risk for infection?
To find out, researchers in Italy conducted a prospective longitudinal study involving 80 premature infants (gestational age ≤32 weeks, birth weight <1500 g) at a neonatal ICU. The infants, born to 68 mothers, were fed fresh milk from their own mothers during the first month of life. Fifty-three …