Invasive Candidiasis in the ICU

Among ICU patients with invasive candidiasis, non-albicans species were isolated in 43%, and reduced fluconazole susceptibility was detected in 17%; most presented with candidemia.

Invasive Candida infections are not uncommon in critically ill patients and are associated with a high risk for death. To assess the current epidemiology, management, and mortality of Candida infections in such patients, researchers (partially supported by industry) conducted a prospective, observational study involving 101 ICUs throughout France. In all, 271 adults with proven invasive candidiasis between October 2005 and May 2006 were included.

Among these patients, 21% were immunocompromised. Thirty-nine percent had isolated candidemia, 28% had invasive candidiasis with candidemia, and 32% had invasive candidiasis without documented candidemia. Eighty-five percent of all episodes were nosocomial. The pathogens most commonly identified wer…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection