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Invasive fungal infections in critically ill patients are worrisome because diagnosis is difficult and the mortality rate is high. Researchers recently developed a “Candida score” (CS) to assess the risk for invasive candidiasis (IC) in such patients. The score was calculated by assigning one point each for total parenteral nutrition, surgery, and multifocal Candida colonization and two points for severe sepsis. Now, the same research group — with partial support from industry — has conducted a prospective observational cohort study to evaluate the CS.
The study involved 1107 nonneutropenic adults treated between April 2006 and June 2007 for ≥7 days in any of 36 medical–surgical ICUs in Spain, Argentina, and France. The mean age of the patie…