AIDS-Associated PCP in the U.S.

Hospital discharge data indicate that hospitalizations for and mortality from AIDS-associated Pneumocystis jirovecii pneumonia have decreased significantly since 1986.

The incidence of opportunistic infections, including Pneumocystis jirovecii pneumonia (PCP), has been greatly reduced among HIV-infected patients in the U.S. by the use of combination antiretroviral therapy (ART) and chemoprophylaxis. Nonetheless, PCP remains an important cause of illness and death — and the most common AIDS-defining condition — in this population.

To examine the changes in AIDS-associated PCP epidemiology over time, researchers analyzed U.S. National Hospital Discharge Survey data for 1986 through 2005. Among the estimated 539 million patients discharged during this 20-year period, approximately 2.2 million had HIV/AIDS. In-hospital mortality of HIV/AIDS patients decreased significantly, from 16% during the prechemoprophyla…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

AIDS-Associated PCP in the U.S.

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Reviewing Author