Central Line Infections and Minocycline/Rifampin–Impregnated Catheters

A longitudinal analysis of central line infection rates at a cancer center's intensive care unit suggests synergy between these antibiotic-impregnated catheters and infection-control precautions.

During the past decade, several strategies have been developed to reduce central line–associated bloodstream infections (CLABSIs) — for example, using maximal sterile barrier precautions during catheter insertion, avoiding unnecessary catheters, and employing catheters impregnated with antiseptics or antibiotics.

To determine the relative effect of various strategies, researchers (1 of whom holds patents related to the antibiotic-impregnated catheters involved in this study) conducted CLABSI surveillance in the medical intensive care unit (MICU) of the MD Anderson Cancer Center. During the 7-year study period, 8009 patients were admitted; CLABSI-reduction measures were instituted sequentially, allowing estimation of their relative benefit. M…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection