Elevated Glucose Levels and Risk for Incident Heart Failure

Researchers assessed this association in a large study of patients at high risk for CVD, including those without diabetes.

People with diabetes are at increased risk for new heart failure (HF), especially when glucose levels are poorly controlled. Are elevated glucose levels associated with incident HF in a broader group of patients at high risk for cardiovascular disease (CVD)?

To find out, researchers analyzed data from more than 30,000 patients (age ≥55) without known HF who were enrolled in two manufacturer-funded, randomized, controlled trials of the angiotensin-receptor blocker telmisartan (ONTARGET and TRANSCEND). All subjects had histories of symptomatic CVD or of diabetes with end-organ damage. Patients were placed in five categories: low-normal fasting plasma glucose (FPG) level (<5.0 mmol/L); high-normal FPG (5.0 mmol/L to <5.6 mmol/L); impaired FPG (…

Reviewing Author

Frederick A. Masoudi, MD, MSPH

Elevated Glucose Levels and Risk for Incident Heart Failure

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Reviewing Author