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Background and Purpose: Morbidity and mortality associated with infective endocarditis (IE) remain high despite great advances in medicine and surgery. Prevention of IE has therefore been a priority for the American Heart Association for more than 50 years. The 2007 document updates the AHA’s guidelines, last revised in 1997. The key rationale for the current revision is to address the persistent question of whether antimicrobial prophylaxis effectively prevents IE associated with dental, gastrointestinal, or genitourinary (GU) tract procedures.
1. Prophylactic antibiotics …