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Diabetes increases the risks for all-cause and cardiovascular-disease mortality. To explore whether hyperglycemia at nondiabetic levels increases such risks as well, investigators from the Australian Diabetes, Obesity, and Lifestyle Study compared outcomes data from participants with normal glucose tolerance (NGT) with those from participants with known diabetes mellitus (KDM), newly diagnosed diabetes (NDM), impaired fasting glucose (IFG), or impaired glucose tolerance (IGT).
Between May 1999 and December 2000, glucose tolerance status was determined for 10,428 participants, who were subsequently followed for a median of 5.2 years. The all-cause mortality rate for the entire cohort was 5.5 per 1000 person-years (298 deaths in all). Overall,…