Favorable Results with Drug-Eluting Stents in Nonbifurcation Left Main PCI

Results from an international registry suggest that DES implantation is safe and effective for treating nonbifurcation ostial and midshaft lesions.

Stent placement in unprotected left main coronary artery (LMCA) lesions is feasible, but long-term results for comparison to surgery have not been available (Journal Watch Cardiology Apr 8 2005). Now, using a multicenter registry, investigators have examined long-term outcomes of drug-eluting stent (DES) implantation in a subset of patients with ostial or midshaft lesions that did not require a bifurcation approach.

A total of 147 patients (19% of all registry patients with LMCA lesions who underwent percutaneous coronary intervention) were treated with sirolimus-eluting (n=107) or paclitaxel-eluting (n=40) stents. The mean age of the 147 patients was 63 years. Intravascular ultrasound was used to guide the procedure in 49% of the patients. …

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI