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Background and Purpose: The pathogenesis of unstable angina (UA) and non–ST-segment-elevation MI (NSTEMI) is similar to that of ST-segment-elevation MI (STEMI): plaque disruption and decreased coronary blood flow, with or without sufficient ischemia to cause myocardial injury. These guidelines, a revision of the 2002 document, provide the evidence base for, and expert opinion on, the best diagnostic and therapeutic strategies for the management of non–ST-segment-elevation acute coronary syndromes. This revisio…