Predicting Long-Term Survival with Exercise Treadmill Testing: A New Model

In an externally validated cohort study, a nomogram that incorporates additional clinical variables was superior to the Duke treadmill score at assessing risk.

Current guidelines for assessing mortality risk in patients with suspected coronary artery disease rely on the Duke treadmill score, which encompasses functional capacity, electrocardiographic indications of ischemia, and exercise–test-induced angina. Now, investigators have developed and externally validated a new post–treadmill-test prediction model, which was derived from variables easily obtained in a stress-testing setting: age; sex; history of smoking, hypertension, diabetes, or typical angina; and exercise-test findings of functional capacity, ST-segment changes, symptoms, heart-rate recovery, and frequent ventricular ectopy during recovery.

A total of 33,268 patients from Cleveland comprised the derivation dataset, and 5821 patients …

Reviewing Author

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute