Results of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy

In a case series in which the type of treatment was determined primarily by patient preference, survival after alcohol ablation was comparable to that after septal myectomy.

Alcohol septal ablation, a relatively new procedure, is performed to alleviate symptoms in patients with hypertrophic obstructive cardiomyopathy (HOCM). In this observational series from the Mayo Clinic, investigators report their experience with this procedure in 138 patients.

Median patient age was 64 (range, 26–86). All had either a resting LV outflow gradient of ≥30 mm Hg (77%) or a provocable gradient of ≥50 mm Hg. The reason cited most often for the decision to perform alcohol ablation instead of surgery was patient choice. The procedure was successful (residual gradient, <20 mm Hg) in 83% of patients. Complications included cardiac tamponade requiring surgery (2 patients), new requirement for pacemaker implantation (28 patients), and …

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI