Estimating Bleeding Risk in Patients with Non–ST-Segment-Elevation MI

A new scoring system could facilitate clinical decision making.

Current treatment of acute non–ST-segment-elevation MI includes both antiplatelet and antithrombotic agents with or without catheter-based interventions, all of which increase the risk for bleeding complications. The CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines) Quality Improvement Initiative investigators developed and validated a model that incorporates eight independent baseline predictors of in-hospital major bleeding in NSTEMI patients enrolled in a U.S. registry.

The median age of the CRUSADE patients was 67, and 60% were men. The rate of major bleeding was 9.4% in the derivation cohort (71,277 patients) and 9.6% in the validation cohort…

Reviewing Author

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute