Coronary Aneurysm After Drug-Eluting Stent Implantation

A prospective case-series study enhances our understanding of a rare complication.

The origins and clinical implications of coronary artery aneurysms (CAAs) that infrequently develop after percutaneous coronary intervention are unclear. In a study of 1197 consecutive patients who underwent late angiographic evaluation after drug-eluting stent (DES) implantation, investigators identified and prospectively followed up 15 patients (1.25%) with CAAs (mean time to CAA diagnosis, 313 days). The angiographic definition of CAA was a localized dilation of DES-related vessel lumen >50% larger than the adjacent reference vessel.

Compared with patients who did not develop CAAs, those who did were more likely to have undergone PCI during MI, had more and longer stents implanted, and more often had residual dissections. In six patients,…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI