Intervention for Non–ST-Segment-Elevation Acute Coronary Syndromes: What Difference Does a Day Make?

Interventions performed immediately or deferred to the next working day resulted in similar outcomes.

The advantages of invasive over conservative strategies for managing non–ST-segment-elevation acute coronary syndromes (NSTEACS) are established, but the optimal timing of intervention is undetermined. To find out whether immediate catheterization compared with delayed intervention reduces incident MI, investigators in France randomized 352 patients hospitalized for NSTEACS to undergo interventional treatment either immediately upon admission or on the next working day (8–60 hours after enrollment).

Median time from randomization to sheath insertion was 70 minutes in the immediate-intervention group and 21 hours in the delayed-intervention group. The primary endpoint, peak troponin level during hospitalization, did not differ significantly b…

Reviewing Author

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)