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Although drug-eluting stents (DES) have reduced the rate of in-stent restenosis (ISR) compared with bare-metal stents, ISR occurs even in some DES recipients. To explore whether stent fractures undetected by coronary angiography might contribute to ISR in these patients, investigators examined 64-detector computed tomographic angiograms (CTA) of 292 patients with 613 stents for partial or complete stent gaps. Each gap was first located visually then confirmed by a radiodensity finding of <300 Hounsfield units, which correlates with the absence of metal, at the site. Coronary angiograms were available for comparison for 143 of the patients.
CTAs showed stent gaps in 14% of all patients. In patients who also had coronary angiograms, gaps were …