Multivessel Interventions for Stable ST-Segment-Elevation Myocardial Infarction: Still a No-Go!

Revascularizing non–infarct-related arteries during primary percutaneous coronary intervention significantly increases 90-day mortality.

Current guidelines discourage revascularization of non–infarct-related arteries (IRAs) during primary or rescue percutaneous coronary intervention (PCI) in patients with stable ST-segment-elevation myocardial infarction (STEMI). However, these recommendations are based on evidence derived from clinical trials with limited power and from the era before routine stenting, platelet glycoprotein inhibition, and clopidogrel pretreatment. In a retrospective analysis of data from the manufacturer-sponsored APEX-AMI trial, investigators identified 5373 STEMI patients undergoing primary PCI and examined the rate of, propensity for, and associated 90-day outcomes of revascularization of non-IRAs during primary PCI.

Of 2201 patients with multivessel dis…

Reviewing Author

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)

Beat J. Meyer, MD

Disclosures

Leadership positions in professional societiesBern Heart Foundation (President); International Academy of Medicine, Bern, Switzerland (Director)