More European Results on Transcatheter Aortic Valve Implantation

Encouraging findings from a study of short-term registry data

Treatment of aortic stenosis with transcatheter aortic valve implantation (TAVI) is becoming routine outside the U.S.; two devices are now available. These investigators report 30-day outcomes in 32 European centers participating in the manufacturer-sponsored SOURCE registry following commercial release of the SAPIEN device.

The cohort included 1038 adults (mean age, 81), 463 of whom received the device transfemorally (TF) and 575 transapically (TA). All patients were at high risk (logistic EuroSCORE, 29% with TA; 26% with TF) for complications of surgical aortic valve replacement (AVR). The procedural success rate was >90%, but important complications included valve embolization (0.3%), coronary obstruction (0.6%), and conversion to surgica…

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI