High-Selenium Yeast Supplements Improve Plasma Lipid Levels

But the effects of this treatment in individuals with normal or high baseline selenium concentrations remain unproven, as do clinical outcomes.

Low selenium concentrations have been linked to increased cardiovascular mortality and morbidity. However, evidence supporting an association between selenium concentration and coronary heart disease risk is ambiguous. To find out more, investigators in the U.K. conducted a randomized, double-blind, parallel-group study involving 501 volunteers, aged 60 to 74, stratified by age and sex. Participants received high-selenium yeast at one of three doses (100, 200, or 300 µg/day) or placebo. At least one lipid measurement was available for 95% of participants at baseline, 6 months, or both.

At baseline, mean plasma selenium concentration was 91.2 µg/L, and higher selenium concentrations were correlated with higher total cholesterol and HDL levels…

Reviewing Author

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

Joel M. Gore, MD

Disclosures

Grant/Research SupportNIH–National Heart, Lung, and Blood Institute

High-Selenium Yeast Supplements Improve Plasma Lipid Levels

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Reviewing Author