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In studies of warfarin, the average time in therapeutic range (TTR) of international normalized ratio (INR) values has ranged from 56% in retrospective studies to 65% in randomized controlled trials. To improve anticoagulation treatment, the Swedish national quality registry for atrial fibrillation (AF) and anticoagulation was founded in 2006. Participating anticoagulation centers use a Web-based dosing algorithm and are located in both primary care and hospital-based settings. These investigators analyzed registry data from 2008 on 18,391 patients (mean age, 70; 40% women) with 250,142 INR samples at 67 centers (mean time between samples per patient, 23 days; mean samples/patient-year, 13.6). Indications for warfarin included AF (64%), ven…