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In the industry-funded PARTNER trial, involving 358 elderly patients with severe aortic stenosis who were not candidates for surgery, transcatheter aortic valve implantation (TAVI) was shown to confer survival and symptom-relief benefits compared with standard therapy (JW Cardiol Sep 22 2010). Investigators now report on health-related quality of life (QOL) among the trial's participants.
At baseline and at 1, 6, and 12 months, assessments were made with the Kansas City Cardiomyopathy Questionnaire (KCCQ), which measures patient-reported, disease-specific health status on a 100-point scale; and with the 12-item Short Form-12 (SF-12) Health Survey. The TAVI and standard-therapy groups both had low mean baseline KCCQ summary and SF-12 scores, …