Off-Pump vs. On-Pump CABG: 30-Day CORONARY Outcomes

Short-term data from the CORONARY trial, which employed experienced surgeons, largely reinforce findings from ROOBY.

Off-pump coronary artery bypass grafting (CABG) was developed to reduce the risk for pump-related adverse events, including diffuse inflammatory response syndrome and stroke due to cannulation of an atherosclerotic aorta. In the Veterans Administration–based ROOBY trial, 30-day outcomes were similar with on-pump and off-pump CABG, and the longer-term need for subsequent revascularization was more common with the off-pump strategy (JW Cardiol Nov 4 2009). However, ROOBY had no expertise requirements for surgeons, raising questions about how well off-pump CABG might fare at more-experienced centers.

In the multinational CORONARY trial, investigators randomized 4752 patients (mean age, 68; 81% men) to undergo either off-pump or on-pump CABG. Al…

Reviewing Author

Frederick A. Masoudi, MD, MSPH, FACC, FAHA

Disclosures

Consultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research

Grant/Research SupportNational Heart, Lung, and Blood Institute

Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)

Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)

Frederick A. Masoudi, MD, MSPH, FACC, FAHA

Disclosures

Consultant/Advisory BoardBristol Myers Squibb; CPC Clinical Research

Grant/Research SupportNational Heart, Lung, and Blood Institute

Editorial BoardsUpToDate; American College of Cardiology Self-Assessment Program (SAP)

Leadership Positions in Professional SocietiesAmerican College of Cardiology (Chair, Innovations Committee)