Discussion on CardioExchange: Uncertainty Over the Clinical Importance of the Diabetes Risk of Diuretics and Statins

To put in perspective some of the controversy over statins and diabetes, Harlan Krumholz points to a study published this week that examined the long-term effects of incident diabetes on cardiovascular outcomes. Compared with patients on amlodipine or lisinopril therapy, those on chlorthalidone therapy had a higher incidence of diabetes but also a lower risk of clinical cardiovascular outcomes. Check out Harlan's analysis and then tell us: Does the cardiovascular reward outweigh the diabetes risk?

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