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The intense pulsed light (IPL) source, with an emission spectrum in the 500-nm to 1200-nm range, has been used for nearly 10 years to treat telangiectasias, pigmented lesions, and photoaging. Because the pulse duration is short, and because the amount of light delivered during treatment is relatively modest, IPL is considered to produce little tissue damage. Investigators studied the truth of this assumption by comparing the effects of IPL, UVA, and UVB irradiation in nine healthy adult volunteers.
Separate skin sites on each volunteer were exposed to a single dose of solar radiation (corresponding to 80 mJ/cm2 UVB radiation), a single dose of 40 J/cm2 UVA radiation, or a single dose of 9 J/cm2 IPL radiation; a fourth control site was unexpo…