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Previous case-control studies suggested an association between endometriosis and melanoma, but the small number of melanomas threw doubt on the significance of the data. A link between melanoma and another disease is clinically relevant by identifying a particular population in whom close screening is warranted.
Investigators prospectively studied risk for melanoma in 98,995 women teachers (age, 40–65) who were enrolled in the Etude Epidémiologique auprès de femmes de la Mutuelle Générale de l’Education Nationale study in France between February 1, 1989, and November 30, 1991. These women, who are covered by a national health plan, have been surveyed every 2 years since entry into the cohort. Women who never menstruated (n=30), those with ca…