Long-term use of nonsteroidal anti-inflammatory drugs was associated with a decreased risk.
Sunscreens, photoprotective clothing, and avoidance of tanning beds and sun exposure have all been advocated to prevent melanoma. Despite these measures, melanoma rates have continued to rise, while the incidence of most malignancies has stabilized or declined. Additional approaches to melanoma prevention are desperately needed.
Prompted by earlier findings suggesting that regular use of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) and statins reduce the development and progression of cutaneous melanoma, investigators performed a case-control study to evaluate the efficacy of aspirin, other NSAIDs, and lipid-lowering agents as chemoprevention. Using patient interviews, the researchers compared drug use in 400 patients, aged 40 or…
Reviewing Author
DisclosuresConsultant / Advisory board Astellas Pharmaceuticals
EquityVaxin
Grant / Research support NIH; NIH/NCI; Veteran’s Administration; Ferndale Laboratories; Kyowa Hakko Kirin Pharma, Inc.
Editorial boards Cancer Prevention Research; Photodermatology, Photoimmunology, & Photomedicine; UpToDate; eMedicine; Journal of Dermatological Sciences; JAMA Dermatology
Leadership positions in professional societies American Academy of Dermatology (Vice Chair, Committee on Science and Research); Photomedicine Society (Board of Directors)
DisclosuresConsultant / Advisory board Astellas Pharmaceuticals
EquityVaxin
Grant / Research support NIH; NIH/NCI; Veteran’s Administration; Ferndale Laboratories; Kyowa Hakko Kirin Pharma, Inc.
Editorial boards Cancer Prevention Research; Photodermatology, Photoimmunology, & Photomedicine; UpToDate; eMedicine; Journal of Dermatological Sciences; JAMA Dermatology
Leadership positions in professional societies American Academy of Dermatology (Vice Chair, Committee on Science and Research); Photomedicine Society (Board of Directors)