Disparity between men and women in survival after melanoma has been well documented; in numerous studies, women appear to fare better than men. The behavior hypothesis suggests that differences in self-awareness, appropriate seeking of medical care, and timely detection influence this observed trend. Alternatively, others propose that hidden biological differences between men and women may explain the difference in prognosis.
These authors conducted an aggregate analysis of data from four large, randomized trials conducted by the European Organisation for Research and Treatment of Cancer (EORTC) Melanoma Group in 2672 patients (48% men) with stage I/II cutaneous disease. Women had a highly persistent and independent advantage in overall surv…
Reviewing Author
DisclosuresConsultant / advisory board Lubax; WorldCare Clinical
EquityLubax
Grant / Research support NIH; Department of Defense; American Skin Association; Piramal
Editorial boardsBritish Journal of Dermatology; Journal of the American Academy of Dermatology; Journal of Investigative Dermatology
Leadership positions in professional societies American Academy of Dermatology (Chair, Skin Cancer and Melanoma Committee); American Board of Dermatology (Director)
DisclosuresConsultant / advisory board Lubax; WorldCare Clinical
EquityLubax
Grant / Research support NIH; Department of Defense; American Skin Association; Piramal
Editorial boardsBritish Journal of Dermatology; Journal of the American Academy of Dermatology; Journal of Investigative Dermatology
Leadership positions in professional societies American Academy of Dermatology (Chair, Skin Cancer and Melanoma Committee); American Board of Dermatology (Director)