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An atypical exanthema (AE) is defined as an eruptive rash morphologically different from the six classical exanthems (measles, scarlet fever, rubella, erythema infectiosum, exanthem subitum, and chicken pox). Although AEs are common, they are diagnostically challenging, and not well studied. To characterize the clinical features and laboratory findings that might help establish the etiology of AEs, investigators studied 260 consecutive patients (108 children, 141 females) with AE who presented to a university dermatology department in Italy. Erythema multiforme patients were excluded.
Seven morphologic patterns emerged: erythema, erythema with macules, erythema with papules, erythema with vesicles, erythema with papules and petechiae, erythe…