Mohs Is Better for DFSP

To evaluate the effectiveness of Mohs micrographic surgery for preventing recurrence of dermatofibrosarcoma protuberans (DFSP), a slow-growing, locally aggressive tumor that rarely metastasizes but is prone to recur after excision, these authors conducted a systematic review of the literature from 1995 to 2011. They sought high-quality, randomized and nonrandomized trials, but because no randomized trials met their criteria, the authors extracted data from 23 nonrandomized trials, which they evaluated using Cochrane Collaboration criteria.

The authors found moderate (level B) evidence indicating that DFSP recurrence was lower after Mohs (1%) than after wide local excision (6%). The median number of Mohs stages required to achieve complete re…